Senior High Performance Computing Engineer

Company: Amgen
Location: Washington
Posted on: June 26, 2025

Job Description:

Join Amgens Mission of Serving Patients At Amgen, if you feel like youre part of something bigger, its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do. Since 1980, weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. As a member of the Amgen team, youll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Senior High Performance Computing Engineer What you will do Lets do this. Lets change the world. In this vital role you will be responsible for the design, integration, and management of high-performance computing (HPC) systems that encompass both hardware and software components into the organizations network infrastructure. This individual will be responsible for all activities related to handling and supporting the Business and platforms including system administration, as well as incorporating new technologies under the challenge of a sophisticated and constantly evolving technology landscape. This role involves ensuring that all parts of a system work together seamlessly to meet the organizations requirements. The candidate will work closely with business stakeholders, to ensure that business needs are considered and met with appropriate technology solutions. Helping to design new solutions to meet changing business needs, is critical to success. The candidate will lead parts of the HPC team through incidents and development cycles ensuring timely communication with all stakeholders to ensure continuous improvements to our operating environment. Roles & Responsibilities: Design, implement, and manage compute and storage infrastructure that supports data science and other scientific workloads, such as computational chemistry, structural biology and image analyses. Collaborate with data scientists and ML engineers to deploy scalable machine learning models into production. Ensure the security, scalability, and reliability of HPC systems both on premise and in the cloud. Optimize cloud resources for cost-effective and efficient use. Drive innovation and stay current with the latest in cloud services and industry standard processes. Provide technical leadership and guidance in cloud and HPC systems management. Develop and maintain CI/CD pipelines for deploying resources to multi-cloud environments. Monitor and fix cluster operations/applications and cloud environments. Document system design and operational procedures. What we expect of you We are all different, yet we all use our unique contributions to serve patients. The professional we seek will have these qualifications. Basic Qualifications: Doctorate degree OR Masters degree and 2 years of Computer Science, IT or related field with hands-on HPC administration experience Or Bachelors degree and 4 years of Computer Science, IT or related field with hands-on HPC administration experience Or Associates degree and 8 years of Computer Science, IT or related field with hands-on HPC administration experience Or High school diploma / GED and 10 years of Computer Science, IT or related field with hands-on HPC administration experience Preferred Qualifications: Must-Have Skills: Demonstrable experience in cloud computing (preferably AWS) and cloud architecture. Experience with containerization technologies (Singularity, Docker) and cloud-based HPC solutions. Experience with infrastructure-as-code (IaC) tools such as Terraform, CloudFormation, Packer, or Ansible Expert with scripting (Python or Bash) and Linux/Unix system administration (preferably Red Hat or Ubuntu). Proficiency with job scheduling and resource management tools (SLURM, PBS, LSF, etc.). Knowledge of storage architectures and distributed file systems (Lustre, GPFS, Ceph). Understanding of networking architecture and security best practices. Good-to-Have Skills: Familiarity with AI/ML algorithms and frameworks (TensorFlow, PyTorch) Experience supporting research in healthcare life sciences. Experience with Kubernetes (EKS) and service mesh architectures. Knowledge of AWS Lambda and event-driven architectures. Exposure to multi-cloud environments (Azure, GCP). Certifications in cloud architecture (AWS Certified Solutions Architect, Google Cloud Professional Cloud Architect, etc.). Experience in an Agile development environment. Prior work with distributed computing and big data technologies (Hadoop, Spark). Professional Certifications: Red Hat Certified Engineer (RHCE) or Linux Professional Institute Certification (LPIC) AWS Certified Solutions Architect Associate or Professional Soft Skills: Strong analytical and problem-solving skills. Ability to work effectively with global, virtual teams Effective communication and collaboration with cross-functional teams. Ability to work in a fast-paced, cloud-first environment. Shift Information: This position requires you to work a Standard Shift with Flexibility to Work Early or Late for Overlap What you can expect from us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, well support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan Stock-based long-term incentives Award-winning time-off plans Flexible work models, including remote and hybrid work arrangements, where possible Apply now and make a lasting impact with the Amgen team. careers.amgen.com In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information. Application deadline Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

Keywords: Amgen, Leesburg , Senior High Performance Computing Engineer, IT / Software / Systems , Washington, Virginia